Alpha2EQ – exclusively available in the UK through MerlinVet UK
Alpha2EQ – exclusively available in the UK through MerlinVet UK
Alpha2EQ is an orthobiologic product treating equine lameness, joint inflammation, soft tissue injury and airway inflammation through AlphaActive filtration technology. Now available exclusively in the UK through MerlinVet UK.

Key Benefits:
- Two-step centrifugation process functionally isolates the alpha-2-macroglobulin from the horse’s own blood
- Powered by patented AlphaActive filtration technology
- Autologous & drug-free
- Laminitis-risk free
- Versatile for horses in all disciplines – from performance to older horses
- Easy on-site processing
- Freezable for up to 12 months
- No competition withdrawal time
- Multi-dose kit suitable for multiple joints in one session
- Observed results – clinical improvement often seen in 7 days, with effects lasting 6–12 months
What is Alpha2EQ?
Alpha2EQ is a drug-free orthobiologic treatment designed to reduce inflammation and support healing in horses. Alpha2EQ isolates a powerful, naturally occurring anti-inflammatory protein called alpha-2-macroglobulin (α2M) from the horse’s own blood using the patented AlphaActive filtration process, to help manage joint pain, soft tissue injuries, and airway inflammation at the source.
The AlphaActive process separates the plasma, then filters and functionally isolates the protein, alpha-2-macroglobulin, a powerful inhibitor of cartilage catabolic factors. When injected or applied to areas of inflammation, alpha-2-macroglobulin removes the damage-causing enzymes to help improve the healing process and protect against further damage. This includes slowing the progression of osteoarthritis by preventing cartilage breakdown and loss.
What Conditions Can Alpha2EQ Help Treat?
Alpha2EQ supports the healing of many inflammatory and degenerative conditions, including:
- Osteoarthritis
- Tendon injuries
- Ligament injuries including suspensory injuries
- Synovitis and bursitis
- Airway inflammation (e.g. equine asthma)
- SI dysfunction
- Prophylactic joint management in performance horses
Common treatment areas include:
Coffin joint, hock, stifle, navicular bursa, suspensory branch, cervical facets, SI joint and more.

Horse Racing animals feet hoofs pounding grass track in a speed running motion action photo.
How Does It Work?
α2M is a large glycoprotein found in the bloodstream. It binds and neutralizes destructive enzymes responsible for cartilage breakdown, joint pain, and inflammation. Due to its size, α2M cannot always reach the areas where it’s needed most. Alpha2EQ solves this by concentrating and delivering α2M directly to affected tissues, promoting healing and protecting against further damage.
The patented AlphaActive filtration process functionally isolates α2M through a two-step centrifugation and filtration method to concentrate and isolate α2M from a small sample of whole blood. This results in a highly purified product that targets inflammation at the source. Unlike other plasma-based products, Alpha2EQ selectively removes harmful plasma proteins, delivering a cleaner, more targeted formulation.
Once isolated, α2M can be injected intra-articularly or applied to affected areas of inflammation to remove damage-causing enzymes and reduce inflammation, improve the healing process and protect against further damage.

How long does Alpha2EQ last?
In most cases, the results of the treatment can be observed within a few days of the procedure and may have long-lasting effects of 6-12 months. Sometimes a series of injections may be needed. Prophylactic use as a chondroprotectant is recommended.
Products available through MerlinVet UK:
- Alpha2EQ Centrifuge
- Alpha2EQ Centrifuge Conversion Kit
- Alpha2EQ 15ml
- Alpha2EQ 30ml
- Alpha2EQ Travel Case
- Centifruge Counter Balance
- Flexineb Nebulizer – Complete Kit


Want to find out more?
Please click here to visit the Alpha2EQ page on the MerlinVet website.
Visit the MerlinVet UK website or contact Marylise:
+447590 714539


